6-deoxy-6-[(5/6)-fluoresceinylthioureido]-HPBCD

6-deoxy-6-[(5/6)-fluoresceinylthioureido]-HPBCD

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6-deoxy-6-[(5/6)-fluoresceinylthioureido]-HPBCD
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Catalog Number CD-DR64
Description The fluoresceinyl moiety is located at C(6). The product is highly hygroscopic and dried to constant weight under 100 mbar vacuum at 50 ˚C. The fluorophore (5/6 isomeric mixture) is attached on the primary hydroxyl rim of the cyclodextrin, via a chemically stable thioureido group. Each cyclodextrin ring contains a fluorescent unit. (2-Hydroxy)propylation is random, but almost exclusively on the secondary hydroxyl rim. The material is water soluble, it dissolves in DMF and DMSO, but it precipitates in acetone.
Molecular Weight 1134.0+n∙(389.4)+m∙(58.1)
Molecular Formula C42H71-n-mNO34 ∙ (C21H12NO5S)n ∙ (C3H7O)m
Solubility (in 100 cm3 solvent, at 25 °C) Water: soluble
Appearance slight yellow to orange powder
Application Chemosensor, fluorescent microscopy, transport processes, host-guest complexation, femtosecond processes.
Storage at 2-8 ˚C temperature, protected from direct light and heat in a tightly closed dark glass container.
Abbreviation FITC-NH-HPBCD
Absorbance λmax: 484 nm
λex: 458 nm
λem: 460 - 650 nm
Cyclodextrin Type Fluorescent cyclodextrins
Impurity Content 6-deoxy-6-monoamino-HPBCD < 20%, free dye < 0.3%
Packaging 1g, 5g, 10g, 25g
Quality fine chemical grade
Substitution By NMR for FITC 0.5 - 1.0
for (2-hydroxy)propyl groups 2.0 - 5.0