Oligo(lactic acid)-β-Cyclodextrin

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Oligo(lactic acid)-β-Cyclodextrin

Catalog CD-DR75

Cyclodextrin Type Cyclodextrin derivatives

Packaging 500 mg, 1 g, 2 g, 3 g, 5 g, 10 g

Storage Condition Store at -20 °C, in tightly closed container

Shelf Life 2 year

Availability In stock

*On-demand pack size is available, please contact us for multi-kilograms pack sizes.

Product Description

Oligo(lactic acid)-β-cyclodextrin (OLA-β-CD) is a specialized derivative of cyclodextrin, resulting from the conjugation of lactic acid moieties with β-cyclodextrin. This compound features the characteristic cyclic structure of cyclodextrin, wherein certain hydroxyl groups have been substituted by lactic acid groups. OLA-β-CD combines the biodegradable properties of OLA with the unique molecular structure of β-CD. β-CD, known for its ability to form inclusion complexes, enhances the molecular encapsulation capabilities of the compound. The incorporation of lactic acid enhances the biocompatibility of OLA-β-CD within biological systems, enabling it to degrade safely and predictably. Moreover, these lactic acid groups play a crucial role in modifying the solubility and molecular recognition properties of the compound, thereby expanding its utility. This compound is commonly used in drug delivery and biomedical applications.

Specification

Characteristics

OLA-β-CD stands out from conventional cyclodextrin derivatives due to its unique and enhanced properties.

• Exceptional biocompatibility. OLA-β-CD boasts exceptional biocompatibility, ensuring it interacts harmoniously with biological systems, which is crucial for applications in drug delivery and tissue engineering.
• Excellent controlled release properties for specific guest molecules. OLA-β-CD exhibits excellent controlled release properties for specific guest molecules. This allows for precise modulation of therapeutic agents, ensuring that active ingredients are delivered in a controlled manner, enhancing therapeutic efficacy while minimizing potential side effects.
• Adjustable water solubility. OLA-β-CD offers adjustable water solubility, a versatile trait that allows it to be tailored to various environmental and chemical conditions, thereby expanding its applicability across diverse fields.

Applications

• Drug development. OLA-β-CD plays a transformative role in the field of drug development by encapsulating hydrophobic drug molecules, thereby significantly enhancing the water solubility of poorly soluble drugs. This encapsulation not only increases the stability of these drugs but also improves their bioavailability, ensuring that more of the active ingredient is available for therapeutic action. By adjusting the substitution degree and position of the lactic acid groups, the release rate and targeting of the drugs can be precisely controlled, allowing for both controlled and sustained release. This precision in drug delivery makes OLA-β-CD an invaluable asset in developing next-generation pharmaceuticals with superior efficacy and reduced side effects.
• Biomedical applications. In the biomedical arena, OLA-β-CD serves as a versatile carrier or functional component within biomedical materials, facilitating controlled drug release and enhancing drug stability and bioavailability. Its potential applications are vast, spanning biomedical imaging, diagnostics, and therapy. For instance, OLA-β-CD can be utilized in targeted drug delivery systems designed specifically for cancer treatment, where it helps deliver therapeutic agents directly to tumor sites, maximizing the therapeutic impact while minimizing adverse effects. This positions OLA-β-CD as a critical tool in advancing personalized medicine and improving the precision and effectiveness of medical treatments.

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It should be noted that our our products and services are for research use only, not for clinical use.