Hyperbranched Cyclodextrin

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Hyperbranched Cyclodextrin

Catalog CD-DR01

Cyclodextrin Type Alkylated cyclodextrin

Packaging 10 kg

Storage Condition Store in a tightly sealed container away from heat and direct light, and in a cool dry place

Shelf Life 2 years

Availability In stock

*On-demand pack size is available, please contact us for multi-kilograms pack sizes.

Product Description

Hyperbranched cyclodextrin, abbreviated as HBCD, is a CD-based hyperbranched polymer designed with CD as a monomer. It contains two different hydrophobic cavities derived from CD and hyperbranched polymers, and has a hyperbranched topography architecture. Therefore, it combines the advantages of CDs and hyperbranched polymers, which not only have the inherent macrocyclic structure and functional hydroxyl groups of CD, but also exhibit polymer properties. The unique structure and properties of HBCD have attracted more and more attention from researchers. It has research prospects and application value in many fields such as water treatment, chiral drug separation, molecular inclusion and recognition, and drug controlled release ^[1].

Specification

Features

HBCD is a polymer system with two different hydrophobic cavities, composed of CD and highly branched polymers. In this section, we list some features of HBCD. These unique features make HBCD more useful for various applications.

Applications

Due to its unique physical and chemical properties, HBCD has aroused great interest of many scientific researchers. A number of studies have been conducted on HBCD, showing that HBCD can be utilized in a wide range of areas. The following are two examples of HBCD's application as a polymer binder in electrochemistry and as an anticoagulant in anticoagulant therapy.

HBCD was used as a polymeric binder in high-capacity silicon (Si) nanoparticle anodes to reduce capacity fading during anode cycling. HBCD contains a series of hydroxyl groups and has a hyperbranched network structure that is able to interact with multi-dimensional hydrogen bonds of Si particles, providing robust contact between the two components. It also helps the Si particles produce a self-healing effect, thereby improving the cycle life of the electrode ^[3].

HBCD was used as an anticoagulant due to its soluble, low/nontoxicity, three-dimensional network, and tunable structure, providing a potential novel anticoagulant treatment. It exhibited the ability to chelate different cationic ions compared to free CDs, which may create a combinatorial effect between the increase in activity of some anticoagulants for complexation and the interference with the Ca²⁺ signal. Furthermore, HBCD performed better than EDTA (a well-known anticoagulant) when analyzing fibrinogen consumption and bleeding time in vivo. All of these confirm the good anticoagulant effect of HBCD and open up new possibilities for its use as a drug carrier for anticoagulant therapy ^[4].

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Alfa Chemistry is one of the world's leading CD manufacturers. Our team of professionals has accumulated extensive expertise in CDs. We offer multi-kilogram quantities of high quality HBCD, tailored to the specific needs of our customers. For more information, please feel free to contact us.

It should be noted that our our products and services are for research use only, not for clinical use.