Gamma-Cyclodextrin Phosphate Sodium Salt

Gamma-Cyclodextrin Phosphate Sodium Salt

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Gamma-Cyclodextrin Phosphate Sodium Salt
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Beta-Cyclodextrin Phosphate Sodium Salt

Abbreviation PGCD26

Catalog CD199684-62-3

CAS Number 199684-62-3

Cyclodextrin Type Cyclodextrin Derivatives

Packaging 1 g, 3 g

Quality Fine chemical grade

Storage Condition Store in an airtight container at room temperature.

Availability In stock

*On-demand pack size is available, please contact us for multi-kilograms pack sizes.

Product Description

Gamma-cyclodextrin phosphate sodium salt is a highly specialized modified cyclodextrin compound, engineered for enhanced solubility, stability, and functionality across a wide range of applications. Gamma-cyclodextrin phosphate sodium salt consists of eight glucopyranose units linked by α-1,4 glycosidic bonds, forming a toroidal molecular structure. The phosphorylation of the hydroxyl groups on the glucose units significantly enhances the compound's ability to interact with hydrophobic molecules, creating a robust hydrophilic outer surface while maintaining a hydrophobic cavity for complexation.

Basic Information

Molecular FormulaC48H80-nO40·(NaHPO3)n
Formula Weight1297.2+n·(102.0)
Possible ImpuritiesGamma-cyclodextrin, disodium hydrogen phosphate
Solubility (in 100 cm3 solvent, at 25 °C)Water: >50 g, Methanol:<1 g, Chloroform: <1 g

Detailed Information

Physical & Chemical Properties

Appearancewhite to slight yellow powder
Average degree of substitution (n)2.0-6.0
Purity>95%
Loss on drying<20%

Impurities

Residual Disodium hydrogen phosphate<0.5%
Residual Gamma-Cyclodextrin<2%

Structural Advantages

  • Enhanced Solubility: The sodium phosphate groups increase the water solubility compared to native cyclodextrins, enabling its use in aqueous environments.
  • Stable Complex Formation: Facilitates the stable inclusion of guest molecules, protecting sensitive ingredients from degradation.
  • Versatility in Modification: Phosphate substitution sites allow further chemical modifications, expanding potential uses.

Applications

  • Pharmaceutical Industry

Gamma-Cyclodextrin Phosphate Sodium Salt is an innovative excipient in drug delivery systems, primarily due to its superior solubilizing and stabilizing properties. Its unique molecular structure enhances the bioavailability of poorly soluble active pharmaceutical ingredients (APIs), promoting efficient drug absorption and therapeutic efficacy.

  • Nutraceuticals and Food Industry

In the nutraceutical sector, Gamma-Cyclodextrin Phosphate Sodium Salt serves as a functional ingredient for encapsulating bioactive compounds, protecting them from environmental degradation, and enhancing their stability and solubility.

  • Cosmetics and Personal Care

Gamma-Cyclodextrin Phosphate Sodium Salt's unique properties make it an ideal ingredient in cosmetic formulations where enhanced delivery and protection of active ingredients are crucial.

  • Industrial Applications

Beyond pharmaceuticals and personal care, Gamma-Cyclodextrin Phosphate Sodium Salt finds uses in various industrial applications where molecular encapsulation, solubility enhancement, and stabilization are required.

Related Products

Alfa Chemistry leverages over two decades of expertise in cyclodextrin chemistry to offer high-quality, customizable gamma-cyclodextrin phosphate sodium salt tailored to your application needs. Our state-of-the-art production facilities and rigorous quality control ensure consistent performance and compliance with the highest industry standards. For more information or to request a quote, please contact us.

It should be noted that our our products and services are for research use only, not for clinical use.