Carboxymethyl-Alpha-Cyclodextrin Sodium Salt - Cyclodextrin / Alfa Chemistry

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Carboxymethyl-Alpha-Cyclodextrin Sodium Salt

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Carboxymethyl-Alpha-Cyclodextrin Sodium Salt

Abbreviation CMACD

Catalog CD-DR02

Cyclodextrin Type Cyclodextrin Derivatives

Packaging 1 g, 10 g, 25 g

Quality Fine chemical grade

Storage Condition Store in an airtight container at room temperature.

Availability In stock

*On-demand pack size is available, please contact us for multi-kilograms pack sizes.

Product Description

Carboxymethyl-alpha-cyclodextrin sodium salt is a chemically modified derivative of alpha-cyclodextrin, a cyclic oligosaccharide composed of six glucose units. The modification involves the introduction of carboxymethyl groups (-CH₂COOH) on the hydroxyl groups of the cyclodextrin, resulting in an anionic character. The sodium salt form enhances its solubility in aqueous environments.

Key Properties

Compared to native cyclodextrins, carboxymethyl-alpha-cyclodextrin sodium salt exhibits significantly higher solubility in water due to its hydrophilic carboxymethyl groups.
Carboxymethyl-alpha-cyclodextrin sodium salt retains the ability to form inclusion complexes with various hydrophobic guest molecules, improving their water solubility and stability. This makes it valuable in the pharmaceutical and cosmetic industries for drug delivery systems and stabilization of active ingredients.
Being a cyclodextrin derivative, carboxymethyl-alpha-cyclodextrin sodium salt is generally considered biocompatible and biodegradable, which is crucial for medical and pharmaceutical applications.

Basic Information

Molecular Formula	C₃₆H_60-nO₃₀·(CH₂COONa)_n
Formula Weight	972.9+n·(80.0)
Possible Impurities	Alpha-cyclodextrin, sodium chloride, chloroacetic acid sodium salt
Solubility (in 100 cm³ solvent, at 25 °C)	Water: >50 g, Methanol:<1 g, Chloroform: <1 g

Detailed Information

Physical & Chemical Properties

Appearance	white to slight yellow powder
Average degree of substitution (n)	3.0-5.0
Purity	>95%
Loss on drying	<10%

Impurities

Residual sodium chloride	<0.1%
Residual 3-chloroacetic acid sodium salt	<0.1%
Residual alpha-cyclodextrin (α-CD)	<2.0%

Applications

Its ability to enhance solubility, bioavailability, and stability of compounds makes carboxymethyl-alpha-cyclodextrin sodium salt a versatile tool across multiple industries.

A. Pharmaceuticals: Used as a solubilizing agent and for enhancing drug bioavailability.

B. Food Industry: Can be applied in food formulations for encapsulating flavors, fragrances, or sensitive nutrients.

C. Cosmetics: Serves as a stabilizer or carrier for volatile and hydrophobic ingredients.

Related Products

As one of the leading CD companies, Alfa Chemistry has a dedicated team that has accumulated extensive expertise in the field of CD chemistry. We offer carboxymethyl-alpha-cyclodextrin sodium salt tailored to meet the requirements of various fields. We do our best to provide customers with first-class products and services. For more information, please feel free to contact us.

It should be noted that our our products and services are for research use only, not for clinical use.