Alpha-Cyclodextrin
Abbreviation ACD
Catalog CD10016203
CAS Number 10016-20-3
Cyclodextrin Type Native, neutral
Packaging 25 kg
Storage Condition Store at room temperature, in tightly closed container
Availability In stock
*On-demand pack size is available, please contact us for multi-kilograms pack sizes.
Product Description
Alpha-cyclodextrin, also abbreviated as α-CD, is a native CD that is derived from glucose. It consists of six d-glucose units linked end to end by α-1-4 linkages, creating a hollow truncated cone or tapered cylinder structure. In the shape of a tapered cylinder, six primary alcohols on one face and twelve secondary alcohol groups on the other. As with other CDs, the outer surface of α-CD is somewhat hydrophilic, whereas the central cavity is hydrophobic. Its functional properties include moderate water solubility, tasteless, odorless, thermal stability, and alkaline and acid stability [1].
Basic Information
| Molecular Formula | C36H60O30 |
| Molecular Weight | 972.9 |
| Possible Impurities | Other cyclodextrins, linear oligomers |
| Solubility (in 100 cm3 solvent, at 25 °C) | Water: > 10 g
Methanol: < 1.0 g
DMSO: > 10 g |
Detailed Information
Physical & Chemical Properties
| Appearance | White or almost white powder |
| Content | 97.0% - 102.0% |
| Appearance of aqueous solution (10 mg/ml) | The solution is clear and colorless. |
| pH | 5.0-8.0 |
| Reducing sugars | Max. 0.2% |
| Loss on drying | Max. 11.0% |
Identification
| Identification: Specific optical rotation | +147 °C to +152 °C |
| Identification: HPLC | Conforms with reference |
| Identification: Iodine test | Yellow-brown precipitate |
Impurities
| Light absorbing impurities (1%) | A230-A350: max. 0.10
A350-A750: max. 0.05 |
| Residual beta-cyclodextrin (β-CD) | Max. 0.25% |
| Residual gamma-cyclodextrin (γ-CD) | Max. 0.25% |
| Other related impurities | Max. 0.50% |
Microorganism
| Total aerobic microbial count (TAMC) | Max. 1000 cfu/g |
| Total yeast and mold count (TYMC) | Max. 100 cfu/g |
Applications
The chemical structure of α-CD can prevent it from being hydrolyzed by human salivary and pancreatic amylases, allowing it as a soluble dietary fiber to be widely used in the field of functional foods [1]. Besides, α-CD also has a certain effect on lowering blood sugar levels and improving the stability of food additives, making it play key roles in health products and food.
- It can be used to improve gastrointestinal function
As a soluble dietary fiber, α-CD can be decomposed by certain normal parasitic bacteria in the intestines and converted into a series of short-chain fatty acids (SCFAs) such as acetic acid, propionic acid, and butyric acid. These SCFAs not only inhibit the growth of harmful bacteria in the intestines, but also help the growth of probiotics such as bifidobacteria, beneficial for improving gastrointestinal function.
- It can be used to lower blood sugar levels
α-CD can be used to inhibit the absorption of sugar in the intestine, promote the excretion of encapsulated sugar, reduce the spike in blood sugar after a high-starch meal, and inhibit the rise in blood sugar after a meal. Therefore, the good blood sugar-lowering effect of α-CD is very useful in preventing and improving diabetes, making it suitable as an effective hypoglycemic health food ingredient.
- It can be used to improve the stability of additives
The compound use of α-CD with vitamin E, natural pigments (such as β-carotene and chlorophyll), food flavors (such as rose oil, and anethole) and other food additives facilitates the preservation of these additives in food and the long-term retention of food flavor.
Related Products
As one of the leading CD companies, Alfa Chemistry has a dedicated team which has accumulated extensive expertise in the field of CD chemistry. We offer high-quality α-CD in multi-kilogram quantities tailored to the special needs of the pharmaceutical and other industries. We do our best to provide customers with first-class products and services. For more information, please feel free to contact us.
Reference
- Câmara, A. K. F. I.; et al. 5.1.5. Alpha-cyclodextrin. Chapter Six - Meat products as prebiotic food carrier. Advances in Food and Nutrition Research. 2020, 94: 223-265.
It should be noted that our our products and services are for research use only, not for clinical use.
