(2-Carboxyethyl)-Alpha-Cyclodextrin
INQUIRY
(2-Carboxyethyl)-Alpha-Cyclodextrin
Abbreviation CEACD
Catalog CD-DR07
Cyclodextrin Type Cyclodextrin Derivatives
Packaging 1 g, 10 g
Quality Fine chemical grade
Storage Condition Store in an airtight container at room temperature.
Availability In stock
*On-demand pack size is available, please contact us for multi-kilograms pack sizes.
Product Description
(2-Carboxyethyl)-Alpha-Cyclodextrin (CE-α-CD) is an advanced derivative of alpha-cyclodextrin, a naturally occurring oligosaccharide known for its ability to form inclusion complexes with a variety of guest molecules. (2-Carboxyethyl)-Alpha-Cyclodextrin is characterized by the addition of a carboxyethyl group to the primary hydroxyl side of the alpha-cyclodextrin ring. This modification enhances its solubility in water and polar solvents and improves its interaction capabilities with various molecules.
Basic Information
| Molecular Formula | C36H60-nO30·(CH2CH2COOH)n |
| Formula Weight | 972.9+n·(72.1) |
| Possible Impurities | Alpha-cyclodextrin, 3-hydroxypropionic acid |
| Solubility (in 100 cm3 solvent, at 25 °C) | Water: >30 g, Methanol:<1 g, Chloroform: <1 g |
Detailed Information
Physical & Chemical Properties
| Appearance | white to slight yellow powder |
| Average degree of substitution (n) | 2.0-4.0 |
| Purity | >95% |
| Loss on drying | <10% |
Impurities
| Residual 3-hydroxypropionic acid | <0.5% |
| Residual alpha-cyclodextrin | <2% |
Features
- The carboxyethyl group significantly improves the water solubility of alpha-cyclodextrin, facilitating its use in aqueous environments.
- The modified structure enhances the binding affinity towards various guest molecules, making it highly effective in encapsulation, drug delivery, and stabilization applications.
- (2-Carboxyethyl)-Alpha-Cyclodextrin retains the inherent non-toxic and biodegradable characteristics of cyclodextrins, making it suitable for use in pharmaceuticals and food industries.
- The presence of reactive functional groups, such as carboxyl and hydroxyl, allows further chemical modification, enabling tailored properties for specific industrial applications.
Applications
Pharmaceutical and Drug Delivery Systems
(2-Carboxyethyl)-Alpha-Cyclodextrin is extensively utilized in drug formulation to enhance the solubility, stability, and bioavailability of active pharmaceutical ingredients (APIs). Its ability to form inclusion complexes with poorly soluble drugs makes it an invaluable excipient in the development of innovative drug delivery systems.
Food and Beverage Industry
In the food industry, CE-α-CD is employed to stabilize flavors, mask undesirable tastes, and enhance the shelf-life of food products. Its non-toxic nature and excellent complexation properties make it ideal for:
- Stabilizes volatile flavors and fragrances, preserving their sensory qualities.
- Protects sensitive nutraceutical ingredients, such as vitamins and antioxidants, from degradation.
Environmental Applications
CE-α-CD's ability to form complexes with organic pollutants makes it a valuable tool in environmental remediation. It can be used in:
- Removes hydrophobic contaminants, such as pesticides and hydrocarbons, from water sources.
- Enhances the extraction of organic pollutants from contaminated soils.
Advanced Materials and Nanotechnology
CE-α-CD is also gaining traction in the field of materials science, where its unique properties are exploited in the design of novel materials:
- Serves as a building block in the synthesis of responsive hydrogels and nanoparticle systems for drug delivery and tissue engineering.
- Contributes to the development of pH-responsive coatings for medical devices and packaging.
Technical Specifications and Quality Assurance
Alfa Chemistry provides CE-α-CD with the highest standards of purity and consistency. Our products undergo rigorous quality control processes, including:
- High-Performance Liquid Chromatography (HPLC)
- Nuclear Magnetic Resonance (NMR) Spectroscopy
- Fourier Transform Infrared (FTIR) Spectroscopy
- Mass Spectrometry (MS)
Our commitment to quality ensures that every batch of CE-α-CD meets or exceeds industry specifications, providing you with a reliable and effective cyclodextrin derivative for your applications.
Related Products
Alfa Chemistry leverages over two decades of expertise in cyclodextrin chemistry to offer high-quality, customizable CE-α-CD tailored to your application needs. Our state-of-the-art production facilities and rigorous quality control ensure consistent performance and compliance with the highest industry standards. For more information or to request a quote, please contact us.
It should be noted that our our products and services are for research use only, not for clinical use.
