Application
The purpose of VPhos Pd G3 is to enhance the efficiency of reductive coupling processes involving non-aromatic heterocyclic alkyl bromides. It achieves this through its novel biaryl(dialkyl)phosphine ligand, which significantly improves the activity profile. Additionally, when used in conjunction with a surfactant system comprising octanoic acid and sodium octanoate, it facilitates Negishi coupling, thereby granting access to a wide range of C(sp3)-C(sp2) cross-coupled products.