Application
The purpose of Tris[N,N,N,N-tetramethylguanidinium][tris(1S)-(1,1-binaphalene)-2,2-diolato]praseodymate Pr-HTMG-B is to serve as a versatile catalyst in facilitating asymmetric reactions. It effectively catalyzes the asymmetric Michael addition of 1,3-dicarbonyls to enones, enhancing the reaction's stereoselectivity. Additionally, it is employed in the asymmetric aza-Michael addition of methylhydroxylamine to chalcone derivatives, as well as in the asymmetric direct aldol reaction involving acetophenone and pivaldehyde, positioning it as a useful tool in asymmetric synthesis.