- Home
- Products
- Phase Transfer Catalysts
- Ammonium Salts
- Tetradecyltrimethylammonium Bromide
Tetradecyltrimethylammonium Bromide
PRICE INQUIRYCatalog Number
ACM1119977-6
Product Name
Tetradecyltrimethylammonium Bromide
Structure
![{[CurrentData.Name]}](https://resource.alfachemic.com/structure/1119-97-7.gif)
CAS
1119-97-7
Synonyms
MTAB; N,N,N-Trimethyl-1-tetradecanammonium bromide; Myristyltrimethylammonium bromide
IUPAC Name
trimethyl(tetradecyl)azanium;bromide
Molecular Weight
336.42
Molecular Formula
C17H38BrN
Canonical SMILES
CCCCCCCCCCCCCC[N+](C)(C)C.[Br-];
InChI
InChI=1S/C17H38N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18(2,3)4;/h5-17H2,1-4H3;1H/q+1;/p-1
InChI Key
CXRFDZFCGOPDTD-UHFFFAOYSA-M
Melting Point
250 °C
Purity
99%
Density
0.5 g/cm³
Solubility
Soluble in water
Appearance
White powder
Storage
+2C to +8C
Complexity
158
Covalently-Bonded Unit Count
2
EC Number
214-291-9
Exact Mass
335.21876
Formal Charge
0
H-Bond Acceptor
1
Heavy Atom Count
19
Isomeric SMILES
CCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
MDL Number
MFCD00011770
Monoisotopic Mass
335.21876
Rotatable Bond Count
13
Topological Polar Surface Area
0 Ų
UNII
8483H94W1E
Application
Tetradecyltrimethylammonium Bromide serves as a versatile compound with multiple applications. It acts as an inhibitor of dynamin I/II by targeting the dynamin-phospholipid interaction, effectively blocking dynamin GTPase activity with a Ki of 940 nM. This functionality allows it to rapidly and reversibly inhibit various forms of endocytosis without causing immediate cellular damage, making it a valuable pharmacological tool for researching dynamin-mediated trafficking events. Additionally, it can induce cytokinesis failure and apoptosis in human cancer cells while also promoting cytoprotective autophagy in human Jurkat T cells. Beyond its biological applications, Tetradecyltrimethylammonium Bromide is used as a disinfectant, deodorant, and laboratory reagent, and it has been employed in studies involving surfactant-controlled synthetic methods and capillary zone electrophoresis to analyze organic acids, thereby highlighting its role as a cationic surfactant in both scientific research and various industrial applications.
February 7, 2025
Highly Effective Research-Grade Inhibitor
Tetradecyltrimethylammonium Bromide from Alfa Chemistry is outstanding for research. It effectively inhibits dynamin GTPase activity, facilitating detailed studies on endocytosis with precise results, making it essential in our laboratory experiments.
- CAS
- Size
- Purity
- Price
- Quantity
- Order
- 1119-97-7
- -
- 99%
- -
-
- +
-
Online Inquiry
※ Please kindly note that our products are for research use only.
