CAS 294-90-6 1,4,7,10-Tetraazacyclododecane - Catalysts / Alfa Chemistry

Synonyms

MLS000069489; Cyclen, 97%; AJ-75747; BP-21532; CHEBI:37391; KRYPTOFIX 11 AZA; EC 425-450-9; 964584YO2O; AM20090388; NCGC00018128-02;

IUPAC Name

1,4,7,10-tetrazacyclododecane;

Molecular Weight

172.276g/mol

Molecular Formula

C8H20N4;

Canonical SMILES

C1CNCCNCCNCCN1;

InChI

InChI=1S/C8H20N4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h9-12H,1-8H2;

InChI Key

QBPPRVHXOZRESW-UHFFFAOYSA-N;

Storage

Refrigerator

Complexity

65.1

Covalently-Bonded Unit Count

EC Number

425-450-9

Exact Mass

172.169g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

172.169g/mol

NSC Number

629374

Topological Polar Surface Area

48.1A^2

UNII

964584YO2O

Application

1,4,7,10-Tetraazacyclododecane, commonly known as Cyclen, is a versatile macrocyclic compound characterized by its almost white to slightly yellow crystalline appearance. This compound is notably soluble in organic solvents like methanol, ethanol, and DMSO, and is derived from Stephania cepharantha. Cyclen is a macrocyclic tetramine with a structure that enables it to selectively bind cations, making it an effective ligand. Its properties allow it to form coordination complexes with metal cations, which is particularly useful in the development of fluorescent nanosensors for detecting metal ions. Additionally, Cyclen serves as a crucial synthetic precursor. Its niche in medical imaging shines through its application in MRI contrast agents, where it functions as a ligand essential for enhancing image clarity. Overall, Cyclen's chemical versatility and binding capabilities extend its utility to numerous scientific and medical fields.

February 12, 2025

Essential Ligand for Precise Metal Ion Detection

Using Alfa Chemistry's 1,4,7,10-Tetraazacyclododecane in our research was excellent. Easily soluble and effective, it served as a crucial ligand in creating fluorescent nanosensors for metal ion detection. Highly recommended for precise scientific applications.