Molecular Weight
219.28
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- tert-Butyl indoline-1-carboxylate
tert-Butyl indoline-1-carboxylate
Catalog Number
ACM143262106-1
Product Name
tert-Butyl indoline-1-carboxylate
Structure
![{[CurrentData.Name]}](https://resource.alfachemic.com/structure/143262-10-6.gif)
CAS
143262-10-6
Application
Tert-butyl indoline-1-carboxylate serves as a pivotal reactant in various synthetic processes. Its primary purpose includes facilitating the preparation of aryl alkyl amines through palladium-catalyzed alkylation reactions and aiding in the synthesis of allyl- and arylindolines. Additionally, it plays a crucial role in the modular indole synthesis of the complex CDEF tetracycle, a key structure in nodulisporic acids A and B. This compound also supports the asymmetric synthesis of β-amino esters via rhodium prolinate complex-catalyzed α-C-H activation and carbenoid insertion reactions. Furthermore, it is utilized in producing substituted indolines and tetrahydroquinolines through a cycloaddition approach, highlighting its versatility as an N-substituted indoline derivative.
February 22, 2025
Highly Effective for Complex Indoline Synthesis
Using tert-Butyl indoline-1-carboxylate in our lab's indoline synthesis was seamless. It significantly facilitated modular assembly, proving essential in creating both allyl and arylindolines efficiently. Highly recommend for complex research applications!
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