CAS 192139-90-5 (S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethanediamine(chloro)(p-cymene)ruthenium(II)

Synonyms

Methyl-4-(1-methylethyl)benzene]-ruthenium; RuCl(p-cymene)[(S,S)-Ts-DPEN]; RuCl(p-cymene)[(R,R)-TsDPEN]; RuCl[(S,S)-Tsdpen](p-cymene)

Molecular Weight

636.21

Molecular Formula

C31H35ClN2O2RuS

Melting Point

>175 °C

Purity

99%

Appearance

Orange brown crystalline powder

Storage

2-8°C

Application

(S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethanediamine(chloro)(p-cymene)ruthenium(II) serves as a versatile and efficient catalyst for several pivotal reactions in the field of asymmetric synthesis. It is primarily employed in the asymmetric transfer hydrogenation of imines and ketones, delivering high enantioselectivity even with functionalized ketones that possess substituents like dialkylamino, hydroxy, siloxy, carbonyl, ester, amide, or thioester groups. Additionally, this compound facilitates intramolecular asymmetric reductive amination and is utilized in tandem hydroformylation/hydrogenation processes of terminal olefins. Beyond its catalytic applications, it has been studied for its role in the thermal decomposition of areneruthenium chiral amido-amine alkyl complexes, highlighting its broad application scope in both catalyst function and reaction mechanism exploration.

February 18, 2025

Highly Effective Catalyst for Asymmetric Hydrogenation

I've used the (S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethanediamine(chloro)(p-cymene)ruthenium(II) from Alfa Chemistry in my research on asymmetric transfer hydrogenation. It performed exceptionally well, precisely delivering enantioselective hydrogenation of imines and ketones.