Application
RuPhos Pd G2 serves as a versatile second-generation precatalyst designed for use in a wide range of palladium-catalyzed cross-coupling reactions, including C-C, C-N, and C-O bond formations, as well as Suzuki-Miyaura coupling reactions. With its biphenyl-based ligand, RuPhos Pd G2 efficiently generates an active palladium catalyst at room temperature when combined with weak phosphate or carbonate bases, making it particularly useful for rapid and efficient Suzuki-Miyaura coupling. Additionally, it is employed in the synthesis of fluoro-substituted diazatetracenes and diazapentacenes through palladium-catalyzed aryl amination reactions, showcasing its significant role in advancing complex molecular constructions.