CAS 155830-69-6 (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine

Synonyms

JOSIPHOS SL-J002-1;(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE;(R)-(-)-1-[(S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-T-BUTYLPHOSPHINE;(R)-(-)-1-[(S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE;(R)-(-)-[(S)-2-(

IUPAC Name

(R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine

Molecular Weight

542.45

Molecular Formula

C32H40FeP2

Purity

96%

Appearance

Orange powder

Exact Mass

542.19500

Application

(R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine is an orange powder that serves as a versatile chiral ferrocenyl diphosphine ligand, extensively utilized in various catalytic processes. It acts as a ligand in palladium-catalyzed reactions, such as the alkoxycarbonylation of 6-bromo-1,4-benzodioxane with sodium tert-butoxide to produce tert-butyl esters, as well as in the amination of aryl halides. Additionally, it is used in rhodium-catalyzed asymmetric processes, including the alcoholysis and aminolysis of oxabenzonorbornadiene, the ring opening of oxabicyclic alkenes with organoboronic acids, and the hydrogenation of enamines. In the realm of copper catalysis, it facilitates asymmetric 1,4-hydrosilylations of α,β-unsaturated esters, while in ruthenium-catalyzed processes, it aids the asymmetric hydrogenation of N-sulfonated-α-dehydroamino acids. Furthermore, it plays a role in palladium-catalyzed Kumada couplings of aryl and vinyl tosylates and the enantioselective synthesis of aryl sulfoxides. Lastly, it enables rhodium-catalyzed enantioselective insertion of a carbenoid carbon into C-C bonds, showcasing its broad applicability in advanced synthetic chemistry.

February 14, 2025

Versatile Ligand for Cutting-Edge Catalysis

I used (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine in asymmetric hydrogenation. This orange powder was invaluable for precise catalysis in my research, enhancing both selectivity and efficiency. Highly recommended for advanced synthetic applications.