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(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol

Catalog Number
ACM22348329
Product Name
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol
Structure
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CAS
22348-32-9
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Synonyms
ZINC3632771; M-1570; FC0554; ANW-24834; CD-407; Diphenyl-Pyrrolidin-2-Yl-Methanol; Jsp004542; AX8016704; diphenyl(2R)-pyrrolidin-2-ylmethanol; AB0005784;
IUPAC Name
diphenyl-[(2R)-pyrrolidin-2-yl]methanol;
Molecular Weight
253.345g/mol
Molecular Formula
C17H19NO;
Canonical SMILES
C1CC(NC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O;
InChI
InChI=1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m1/s1;
InChI Key
OGCGXUGBDJGFFY-MRXNPFEDSA-N;
Complexity
261
Covalently-Bonded Unit Count
1
Defined Atom Stereocenter Count
1
Exact Mass
253.147g/mol
H-Bond Acceptor
2
H-Bond Donor
2
Heavy Atom Count
19
Monoisotopic Mass
253.147g/mol
Rotatable Bond Count
3
Topological Polar Surface Area
32.3A^2
Application
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol serves as a crucial component in the preparation of oxazaborolidines, which are then utilized in the borane-mediated asymmetric reduction of ketones. This compound typically appears as a white to faintly yellow crystalline powder, ensuring its suitability for various chemical reactions, including the Suzuki reaction, thereby broadening its application in the synthesis of fine chemicals and pharmaceuticals.
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