CAS 53189-26-7 Palladium(II) Acetate Trimer - Catalysts / Alfa Chemistry

Synonyms

53189-26-7;palladium(ii) acetate trimer;EINECS 258-424-9;Hexakis(mu-(acetato-O:O'))tripalladium;MFCD00064617;

IUPAC Name

acetic acid;palladium;

Molecular Weight

679.572g/mol

Molecular Formula

C12H24O12Pd3;

Canonical SMILES

CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.[Pd].[Pd].[Pd];

InChI

InChI=1S/6C2H4O2.3Pd/c6*1-2(3)4;;;/h6*1H3,(H,3,4);;;;

InChI Key

FUKTVTHLBVPABW-UHFFFAOYSA-N;

Complexity

78.6

Covalently-Bonded Unit Count

EC Number

258-424-9

Exact Mass

678.839g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

677.837g/mol

Topological Polar Surface Area

224A^2

Application

Palladium(II) Acetate Trimer, presented as brown needles, is a versatile compound primarily used in Suzuki-Miyaura cross-coupling reactions and as a catalyst for intramolecular coupling. It plays a crucial role in catalyzing the chemoselective reduction of nitroarenes and acts as a homogeneous oxidation catalyst, which activates alkenic and aromatic compounds for oxidative inter- and intramolecular nucleophilic reactions. The trimeric structure of palladium(II) acetate, with symmetry D3h, features double acetate bridges connecting the palladium atoms. It is also effective in microencapsulation using polyurea, enhancing its use as a heterogeneous catalyst in phosphine-free cross-coupling and Heck reactions, specifically for arylation of olefins. The compound is soluble in benzene and toluene, yet insoluble in ether and alcohol, and should be stored in the dark and refrigerated to maintain its efficacy. Additionally, it serves as a catalyst for C-H activation and as a precatalyst for enantioselective decarboxylative protonation of allyl β-ketoesters.

January 27, 2025

Highly Effective Catalyst for Cross-Coupling

Palladium(II) Acetate Trimer from Alfa Chemistry has proven invaluable in our research, especially in Suzuki-Miyaura reactions. Its solubility profile is excellent, facilitating seamless usage. Highly recommended for C-H activation studies.