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N-((S)-1-((4S,5S)-4-Benzyl-5-phenyl-4,5-dihydrooxazol-2-yl)-2,2-dimethylpropyl)acetamide

Catalog Number
ACM2079094327
Product Name
N-((S)-1-((4S,5S)-4-Benzyl-5-phenyl-4,5-dihydrooxazol-2-yl)-2,2-dimethylpropyl)acetamide
CAS
2079094-32-7
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  • Usage
Molecular Weight
364.48
Storage
2-8°C
Application
N-((S)-1-((4S,5S)-4-Benzyl-5-phenyl-4,5-dihydrooxazol-2-yl)-2,2-dimethylpropyl)acetamide serves as a specialized chiral ligand developed by Jin-Quan Yu's laboratory to aid in Pd(II)-catalyzed enantioselective β-C(sp3)H functionalizations, such as arylation, alkenylation, and alkynylation. This mono-protected aminomethyl oxazoline (MPAO) ligand is specifically utilized for the complex desymmetrization of isopropyl groups, thereby facilitating advanced synthetic transformations in organic chemistry.
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