Application
Methanesulfonato(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II), also known as XPhos Palladacycle Gen. 4, serves as a robust catalyst designed to facilitate classic cross-coupling reactions. This compound, which is a stable powder that dissolves readily in most organic solvents, integrates the Buchwald Fourth Generation Palladacycle to enhance its effectiveness. Notably, it is particularly effective for the Suzuki-Miyaura coupling, making it ideal for working with unstable boronic acids, thus expanding the scope and efficiency of modern organic synthesis.