Iso Desloratadine

Catalog Number
ACM432543890
Product Name
Iso Desloratadine
Structure
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CAS
432543-89-0
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Synonyms
8-Chloro-6,11-dihydro-11-(1,2,3,6-tetrahydro-4-pyridinyl-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Monohydrochloride
Molecular Weight
347.28
Molecular Formula
C19H20Cl2N2
Melting Point
>155° C (dec.)
Storage
2-8°C storage
Application
Iso Desloratadine serves as an impurity found in Desloratadine, which is known for its role as a non-sedating histamine H1-receptor antagonist. As an active metabolite of Loratadine, Desloratadine effectively inhibits the generation and release of inflammatory mediators from basophils and mast cells. Iso Desloratadine is also identified as an impurity formed during the synthesis of Rupatadine, highlighting its significance in understanding and managing the quality of pharmaceutical products.
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