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4-(2-Iodoacetamido)-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

Catalog Number
ACM25713240-1
Product Name
4-(2-Iodoacetamido)-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical
Structure
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CAS
25713-24-0
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Synonyms
4-(2-Iodoacetamido)-TEMPO Free Radical
Molecular Weight
339.2
Molecular Formula
C11H20IN2O2
Canonical SMILES
CC1(CC(CC(N1[O])(C)C)NC(=O)CI)C
InChI
InChI=1S/C11H20IN2O2/c1-10(2)5-8(13-9(15)7-12)6-11(3,4)14(10)16/h8H,5-7H2,1-4H3,(H,13,15)
InChI Key
UCTVRHAKQRFPEZ-UHFFFAOYSA-N
Melting Point
127 °C
Purity
>98.0%(HPLC)
Appearance
Light yellow to Amber to Dark green powder to crystal
Storage
Store at 2-8°C, filled with argon
Complexity
261
Covalently-Bonded Unit Count
1
Exact Mass
339.05695g/mol
Formal Charge
0
H-Bond Acceptor
2
H-Bond Donor
1
Heavy Atom Count
16
MDL Number
MFCD00010171
MeSH Entry Terms
2,2,6,6-tetramethylpiperdin-N-1-oxyiodoacetamide;4-(2-iodoacetamido)-2,2,6,6-tetramethylpiperidine-1-oxyl;4-(N-iodoacetamide)-2,2,6,6-tetramethylpiperidine-1-oxyl;IASL;N-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide;N-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide;N-(oxyl-2,2,6,6-tetramethylpiperid-4-yl)iodoacetamide;TMPIA
Monoisotopic Mass
339.05695g/mol
Rotatable Bond Count
2
Application
The purpose of 4-(2-Iodoacetamido)-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical is to serve as a methionine-specific spin label, facilitating the investigation of binding sites, specifically for phosphoenolpyruvate carboxykinase and GTP. Additionally, it plays a role in assessing the alkylation processes of SH1 and SH2 in myosin.
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