CAS 496-15-1 Indoline - Catalysts / Alfa Chemistry

Synonyms

AI3-39164; 15617-EP2311829A1; 2,3-dihydro-1 H-indole; aza-indane; 27157-EP2314575A1; Indoline, Vetec(TM) reagent grade, 98%; AC1Q1H8F; DTXSID9052133; 15617-EP2295429A1; 15617-EP2305648A1;

IUPAC Name

2,3-dihydro-1H-indole;

Molecular Weight

119.167g/mol

Molecular Formula

C8H9N;

Canonical SMILES

C1CNC2=CC=CC=C21;

InChI

InChI=1S/C8H9N/c1-2-4-8-7(3-1)5-6-9-8/h1-4,9H,5-6H2;

InChI Key

LPAGFVYQRIESJQ-UHFFFAOYSA-N;

Solubility

0.09 M;

Storage

2-8°C

Complexity

101

Covalently-Bonded Unit Count

EC Number

207-816-8

Exact Mass

119.073g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

119.073g/mol

Topological Polar Surface Area

12A^2

UNII

6DPT9AB2NK

Application

Indoline, a versatile colorless liquid with the chemical formula C8H9N, is pivotal in the synthesis of a variety of medicinal compounds due to its nature as an indole derivative. With a boiling point of 229 - 230 ℃ at standard pressure, it is soluble in diethyl ether, acetone, and benzene, yet only slightly soluble in water. Indoline is typically produced through the hydrogenation of indole or via the catalytic cyclodehydration of 2-(2-aminophenyl)ethanol. Its utility spans the pharmaceutical industry, notably in developing α1-adrenoceptor antagonists, as well as fungicides and bactericides. Furthermore, indoline and its derivatives are integral in crafting perfumes, dyes, agrochemicals, and serve as reactants in producing a wide array of bioactive compounds, inhibitor agents, and receptor modulators, contributing significantly to advancements in medical and biochemical fields.

January 20, 2025

Indoline: Versatile and Essential for Research

Indoline has been indispensable in our research for synthesizing potential α1-adrenoceptor antagonists. Its solubility in various solvents makes it perfect for reactions. Reliable and efficient product - highly recommended for pharmaceutical applications!