CAS 527-09-3 Gluconic acid copper(II) salt, 98%

Synonyms

Chelates of copper gluconate; KS-00000WNP; DB11246; D-Gluconicacidcopper(II)salt; HSDB 261; Copper gluconate (USP); Copper gluconate [USP]; Copper(II) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate; AN-45570; SCHEMBL23076;

IUPAC Name

copper;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate;

Molecular Weight

453.84g/mol

Molecular Formula

C12H22CuO14;

Canonical SMILES

C(C(C(C(C(C(=O)[O-])O)O)O)O)O.C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[Cu+2];

InChI

InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1;

InChI Key

OCUCCJIRFHNWBP-IYEMJOQQSA-L;

Melting Point

155-157 deg C /D-form/;

Solubility

Sol in water; insol in acetone, alcohol, ether;

Color Form

Light blue crystalline powder;

Complexity

165

Covalently-Bonded Unit Count

Defined Atom Stereocenter Count

EC Number

208-408-2

Exact Mass

453.031g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

453.031g/mol

Odor

Odorless;

Other Experimental

Light blue to bluish-green, odorless crystals and crystalline powder. Astringent taste. 30 g soluble in 100 ml water at 25 deg C; slightly sol in alcohol; practically insol in most org solvents. /Hydrate/;

Rotatable Bond Count

Topological Polar Surface Area

283A^2

UNII

RV823G6G67

Application

Gluconic acid copper(II) salt, with a purity of 98%, serves a multifaceted role as a dietary supplement due to its foundation as the copper salt of D-gluconic acid, which is a significant organic acid. Recognized for its essential role in human and animal health, it aids in the absorption of ions from the gut and plays a crucial part in regulating blood pressure and heart rate. This compound acts as a buffer to encapsulate drugs within liposomes and is an important copper supplement to address conditions like copper deficiency anemia and nephrosis. With its involvement in enhancing the effectiveness of the anticancer drug disulfiram, it is beneficial in cancer chemotherapy. Additionally, Gluconic acid copper(II) salt finds applications in the treatment of various conditions such as acne vulgaris, the common cold, hypertension, premature labor, leishmaniasis, and visceral postoperative complications. Its utility extends further into nutritional supplementation as a synergist for foods, oral deodorants, and feed additives, and as the active ingredient in certain mints and breath fresheners, demonstrating skin-conditioning and skin-protecting properties.

January 25, 2025

Effective Buffering Agent for Drug Encapsulation

I used Alfa Chemistry's Gluconic acid copper(II) salt, 98% in my research to encapsulate drugs into liposomes. It enhanced efficacy in our cancer chemotherapy experiments. Excellent solubility and reliability in all applications.