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Ethyl 2-methyl-3-indoleacetate

Catalog Number
ACM21909499-1
Product Name
Ethyl 2-methyl-3-indoleacetate
Structure
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CAS
21909-49-9
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Synonyms
2-methylindole-3-acetic acid; NSC 289352
Molecular Weight
217.26
Boiling Point
195-196° C (lit.) at 3.5 mmHg
Density
1.11 g/mL at 25° C
Storage
room temperature
Application
Ethyl 2-methyl-3-indoleacetate, also known as ethyl 2-(2-methyl-1H-indol-3-yl)acetate, serves as a crucial reactant in pharmaceutical chemistry. It is primarily used in the preparation of hydroxamate derivatives, which function as HDAC inhibitors exhibiting anticancer activity. Additionally, it plays a significant role in the stereoselective synthesis of AG-041R, a potent antagonist of the Gastrin/CCK-B receptor.
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