Application
The 4-Diphenylphosphinomethyl Polystyrene Resin cross-linked with 2% DVB (200-400 mesh) (0.5-1.0 mmol/g) serves as a versatile functional support for solid-phase synthesis, particularly in the realm of organic chemistry applications. This specialized resin can be effectively modified by reacting it with carboxylic acid-containing linkers through standard amide bond formation techniques, thereby creating supports optimal for Boc and Fmoc batch processes. Besides its primary role in synthesis, this resin, characterized by its unique phosphinomethyl functionalization, can act as a macromolecular agent supporting the conjugation with enzymes, proteins, and other bioactive molecules. This adaptability and efficiency make the resin instrumental in the development of well-defined assemblies in various chemical environments, enhancing the precision and scope of synthetic transformations.
