CAS 17261-28-8 2- diphenylphosphino benzoic acid

Synonyms

o-Diphenylphosphinobenozic acid; VZ23287; CTK3J1542; BCP18923; N058; CHEMBL361405; W-110451; 261D288; ANW-22590; 17261-28-8;

IUPAC Name

2-diphenylphosphanylbenzoic acid;

Molecular Weight

306.301g/mol

Molecular Formula

C19H15O2P;

Canonical SMILES

C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3C(=O)O;

InChI

InChI=1S/C19H15O2P/c20-19(21)17-13-7-8-14-18(17)22(15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H,(H,20,21);

InChI Key

UYRPRYSDOVYCOU-UHFFFAOYSA-N;

Complexity

340

Covalently-Bonded Unit Count

EC Number

241-293-7

Exact Mass

306.081g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

306.081g/mol

Rotatable Bond Count

Topological Polar Surface Area

37.3A^2

Application

2-Diphenylphosphino benzoic acid, appearing as a light yellow powder, serves a crucial role in the realm of biochemical research. Its primary purpose is to facilitate the small molecule control of protein function through a process known as Staudinger reduction. The compound is central to synthesizing complex ligands, such as (R,R)-1,2-bis(aminocarbonylphenyl-2'-diphenylphosphino)cyclohexane, which are essential in various chemical reactions and studies. The synthesis of such ligands typically involves coupling this benzoic acid with other compounds, utilizing reagents like DCC or through alternative methods involving mixed anhydrides. Through its applications, 2-diphenylphosphino benzoic acid demonstrates its importance in advancing the understanding and manipulation of protein functions in scientific research.

December 05, 2024

Essential Reagent in Catalysis Research

2-Diphenylphosphino benzoic acid is a key component in our catalysis experiments. Its efficiency and reliability in the lab are unmatched, facilitating seamless coupling processes and enhancing reaction yields considerably. Highly recommended for robust scientific applications.