Di( µ -chloro)bis(1,5-cyclooctadiene)diiridium(I)

Application

Di(µ-chloro)bis(1,5-cyclooctadiene)diiridium(I) serves as a versatile precursor to a wide range of iridium complexes used in homogeneous catalysis. This red-orange solid plays a crucial role in enabling a variety of chemical transformations, including carbonylation, hydrosilylation, hydroformylation, asymmetric allylic substitutions, metathesis, and chiral catalysis reactions. Additionally, it is instrumental in the synthesis of Crabtree's catalyst, a well-known catalyst for hydrogenation and hydrogen-transfer processes. Specifically, its applications extend to facilitating the asymmetric hydrogenation of tri- and tetrasubstituted olefins, enantioselective reduction of imines, allylic alkylation, amination, and etherification, as well as reactions involving aroyl chlorides and alkynes to form substituted naphthalenes and anthracenes. Its catalytic capabilities further include Ir-catalyzed acid chloride additions to terminal alkynes, intramolecular hydroamination with secondary alkyl- and arylamines, enantioselective [2+2] cycloadditions, silyl-directed ortho-borylation of arenes, cross-coupling of styrene derivatives with allylic carbonates, and transfer hydrogenative C-C coupling, making it an indispensable component in advanced synthetic chemistry.