(1,5-Cyclooctadiene)(methoxy)iridium(I) Dimer

Application

The (1,5-Cyclooctadiene)(methoxy)iridium(I) dimer serves as an efficient catalyst in various chemical processes. Its key applications include facilitating the synthesis of heteroaryl fused indole ring systems, which are critical for the inhibition of HCV NS5B polymerase. It also plays a vital role in borylation and Suzuki-Miyaura coupling reactions. Beyond these, it is employed in tetraborylation reactions and the ortho-silylation of aryl ketone, benzaldehyde, and benzyl alcohol derivatives through C-H activation. The most notable application is its ability to selectively perform asymmetric hydroboration with high regio and enantioselectivity. Additionally, it acts as a potent C-H activation catalyst for the conversion of arenes into phenols.