Chloro(1,5-cyclooctadiene)iridium(I) dimer

Application

The compound Chloro(1,5-cyclooctadiene)iridium(I) dimer, characterized by its red-orange solid form, serves as a versatile precursor to a variety of iridium complexes used extensively in homogeneous catalysis. This compound is essential in facilitating numerous catalytic reactions, including carbonylation, hydrosilylation, hydroformylation, and asymmetric allylic substitutions, as well as metathesis and chiral catalysis. It plays a pivotal role in the synthesis of Crabtree's catalyst, utilized in hydrogenation and hydrogen-transfer reactions. The product is crucial for developing catalysts used in specific processes such as asymmetric hydrogenation of tri- and tetrasubstituted olefins, enantioselective reduction of imines, allylic alkylation, allylic amination and etherification, as well as the conversion of aroyl chlorides with internal alkynes into substituted naphthalenes and anthracenes. Furthermore, it facilitates the Ir-catalyzed addition of acid chlorides to terminal alkynes and promotes intramolecular hydroamination of unactivated alkenes with secondary alkyl- and arylamines. It is also instrumental in enantioselective [2+2] cycloaddition, silyl-directed ortho-borylation of arenes, cross-coupling of styrene derivatives with allylic carbonates, and transfer hydrogenative C-C coupling, showcasing its broad applicability and importance in advanced chemical synthesis.