Chloro(4-cyanophenyl)[(R)-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylditertbutylphosphine]nickel(II)

Application

Chloro(4-cyanophenyl)[(R)-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylditertbutylphosphine]nickel(II) serves as a versatile, air-stable, and cost-effective nickel catalyst that provides an alternative to palladium for facilitating carbon-carbon and carbon-heteroatom cross-coupling reactions. This product is particularly useful for transforming substituted aryl and heteroaryl halides and tosylates into a variety of aryl and heteroaryl amines through reactions with ammonia. It also supports monoarylation experiments utilizing commercially available ammonia gas, ammonium salts, or ammonia stock solutions, and excels in catalyzing the coupling of aryl chlorides with amines in the form of their hydrochloride salts, enabling efficient amination of aryl chlorides with ammonia.