CAS 62965-35-9 Boc-Tle-OH - Catalysts / Alfa Chemistry

Synonyms

AB0001018; 169870-82-0; 62965-35-9; AB1007224; AC-24090; J-300341; N-BOC-L-tert-Leucine, 98%; AN-32679; (S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid; (s)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoic acid;

IUPAC Name

(2S)-3,3-dimethyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid;

Molecular Weight

231.292g/mol

Molecular Formula

C11H21NO4;

Canonical SMILES

CC(C)(C)C(C(=O)O)NC(=O)OC(C)(C)C;

InChI

InChI=1S/C11H21NO4/c1-10(2,3)7(8(13)14)12-9(15)16-11(4,5)6/h7H,1-6H3,(H,12,15)(H,13,14)/t7-/m1/s1;

InChI Key

LRFZIPCTFBPFLX-SSDOTTSWSA-N;

Storage

Store at RT.

Complexity

273

Covalently-Bonded Unit Count

Defined Atom Stereocenter Count

EC Number

613-118-8

Exact Mass

231.147g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

231.147g/mol

Rotatable Bond Count

Topological Polar Surface Area

75.6A^2

Application

Boc-Tle-OH is a white to slightly yellow crystalline powder designed for the synthesis of amino acid drugs, taking advantage of its versatile amine and carboxyl group reactivity. As a derivative of L-tert-Leucine, a non-polar amino acid, Boc-Tle-OH features a Boc protective group that safeguards the amino group from non-specific reactions. Its tert-butyl group offers notable hydrophobicity and steric hindrance, which aids in controlling molecular conformation during chemical reactions and facilitates the formation of chiral compounds. This compound is instrumental as a chiral intermediate in producing anti-cancer, anti-viral, and biological inhibitors, and also proves valuable in the food and cosmetic industries as a key additive.

February 8, 2025

Boc-Tle-OH: A Reliable Research Ally

Boc-Tle-OH's steric hindrance effectively aids amino acid drug synthesis. Its protective group ensures specificity, crucial in chiral compound production. Straightforward in application, it's essential for research precision and efficiency.