CAS 12083-48-6 Bis(cyclopentadienyl)vanadium dichloride

Synonyms

Dichlorovanadocene, Cl2-vanadocene, Vanadocene dichloride, Vanadinocene Dichloride, CCRIS 5975, Bis(cyclopentadienyl)vanadium chloride, EINECS 235-150-8, Dichlorodi-pi-cyclopentadienylvanadium, AIDS001312, AIDS-001312, CID82917, Vanadium, dichlorodi-pi-cyclopentadienyl-, LS-2091, Bis(cyclopentadienyl)vanadium Dichloride, NCGC00091742-01, BIS(CYCLOPENTADIENYL)VANADIUMCHLORIDE, V0090, Dichlorobis(.eta.5-cyclopenta-2,4-dien-1-yl)vanadium, Vanadium, dichlorobis(eta5-2,4-cyclopentadien-1-yl)-, 12083-48-6

IUPAC Name

cyclopenta-1,3-diene; dichlorovanadium

Molecular Weight

252.03

Molecular Formula

(C₅H₅)₂VCl₂

InChI Key

UMGIRDUNLQIEBM-UHFFFAOYSA-L

Boiling Point

41.5ºC at 760 mmHg

Melting Point

182-194ºC (dec.)(lit.)

Purity

96%

Density

1.6 g/cm³

Exact Mass

250.96000

H-Bond Acceptor

H-Bond Donor

Application

Bis(cyclopentadienyl)vanadium dichloride is a versatile compound widely utilized for its catalytic properties and potential therapeutic applications. As a catalyst, it facilitates the preparation of vicinal amino alcohols, oligomerization reactions via the Aufbau propagation reaction, aqueous polymerization using oxygen as a co-catalyst, and dl-selective pinacol-type coupling reactions. It also plays a role in influencing the crystal growth of calcium carbonate. In addition to these uses, it serves as an inhibitor of human topoisomerase II enzyme, demonstrating significant antitumor activity and showing promise as a developmental anticancer agent. This dark green crystalline powder is highly reactive, with a strong sensitivity to air and moisture, decomposing in water and requiring careful handling to avoid generating toxic or flammable gases. Its structure contains a vanadium center with an oxidation state of +IV, and it features a 17-electron complex that is paramagnetic, contributing to its effectiveness as an antiproliferative agent in preclinical testing.

December 07, 2024

Versatile Catalyst for Research Applications

Bis(cyclopentadienyl)vanadium dichloride, a dark green powder from Alfa Chemistry, proved exceptional in catalyzing polymerization and coupling reactions. Its reactivity and sensitivity necessitate careful handling, but its effectiveness is outstanding in research applications.