CAS 979-88-4 BCA Disodium - Catalysts / Alfa Chemistry

Synonyms

Sodium [2,2'-biquinoline]-4,4'-dicarboxylate; [2,2'-Biquinoline]-4,4'-dicarboxylic acid, disodium salt

IUPAC Name

disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-4-carboxylate

Molecular Weight

388.28

Molecular Formula

C20H10N2Na2O4

Canonical SMILES

C1=CC=C2C(=C1)C(=CC(=N2)C3=NC4=CC=CC=C4C(=C3)C(=O)[O-])C(=O)[O-].[Na+].[Na+]

InChI

AUPXFICLXPLHBB-UHFFFAOYSA-L

InChI Key

InChI=1S/C20H12N2O4.2Na/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);;/q;2*+1/p-2

Boiling Point

530.6 °C at 760 mmHg

Melting Point

300 °C

Purity

96%

Appearance

White to light yellow powder

Storage

2-8°C

Complexity

495

Covalently-Bonded Unit Count

Exact Mass

388.04359537

H-Bond Acceptor

Heavy Atom Count

Monoisotopic Mass

388.04359537

Rotatable Bond Count

Topological Polar Surface Area

106 Å²

Application

BCA Disodium serves as a versatile colorimetric reagent primarily utilized for detecting copper ions (Cu+) through its formation of a stable 2:1 complex with these ions, displaying a maximum absorbance at 562 nm. Widely applied in the BCA protein quantitation assay, this reagent facilitates the conversion of Cu2+ to Cu+ in response to protein concentration changes under alkaline conditions. Additionally, BCA Disodium is invaluable for determining protein concentration and monitoring reducing sugars, such as in the detection of chitinases and the quantification of cellulose reducing ends. Renowned for its photometric capabilities, it offers sensitivity akin to neocuproin, making it an essential component in various biochemical assays and analyses.

January 12, 2025

Excellent Reagent for Protein and Copper Quantitation

Having used BCA Disodium from Alfa Chemistry, I'm impressed with its precision in protein and copper assays. The colorimetric response at 562 nm offers reliable data, enhancing our research efficiency and accuracy. Highly recommended for lab use!