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1,2-Bis[(2R,5R)-2,5-dimethylphospholano]ethane

Catalog Number
ACM129648073
Product Name
1,2-Bis[(2R,5R)-2,5-dimethylphospholano]ethane
Structure
1,2-Bis[(2R,5R)-2,5-dimethylphospholano]ethane
CAS
129648-07-3
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Synonyms
Phospholane, 1,1'-(1,2-ethanediyl)bis(2,5-dimethyl-, (2R,2'R,5R,5'R)-; (+)-1,2-Bis(2R,5R)-2,5-dimethylphospholano)ethane; MFCD01073770; 1,2-Bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane; SCHEMBL3688560; ZINC2572357; Me-bpe, (R,R)-; (R,R)-Me-bpe, (+)-; (S,S)-Me-en-duphos; 1,2-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]ethane;
IUPAC Name
(2R,5R)-1-[2-[(2R,5R)-2,5-dimethylphospholan-1-yl]ethyl]-2,5-dimethylphospholane;
Molecular Weight
258.326g/mol
Molecular Formula
C14H28P2;
InChI
InChI=1S/C14H28P2/c1-11-5-6-12(2)15(11)9-10-16-13(3)7-8-14(16)4/h11-14H,5-10H2,1-4H3/t11-,12-,13-,14-/m1/s1;
InChI Key
IRCDUOCGSIGEAI-AAVRWANBSA-N;
Complexity
185
Covalently-Bonded Unit Count
1
Defined Atom Stereocenter Count
4
Exact Mass
258.167g/mol
Heavy Atom Count
16
Monoisotopic Mass
258.167g/mol
Rotatable Bond Count
3
Topological Polar Surface Area
0A^2
UNII
1LS1AFH1F1
Application
The DUPHOS family of catalysts is highly efficient for the asymmetric hydrogenation of various substituted acetamidoacrylates and enol acetates yielding products of high enantiomeric excesses. Efficient ligand for the asymmetric hydrogenation of tetrasubstituted enamides.
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