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1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene

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Catalog Number
ACM312959243-2
Product Name
1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene
Structure
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CAS
312959-24-3
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Synonyms
Q-PHOS; CTC-Q-PHOS; 1,2,3,4,5-pentaphenyl-1-di-tert-butylphosphinoferrocene; 1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene;
IUPAC Name
1,2,3,4,5-PENTAPHENYL-1-(DI-TERT-BUTYLPHOSPHINO)FERROCENE
Molecular Weight
710.72
Molecular Formula
C48H47FeP
Melting Point
211-219ºC
Purity
96%
Exact Mass
710.27600
Application
1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene is a phosphine ligand characterized by its steric hindrance, designed to enhance the efficiency of palladium-catalyzed reactions. This pink solid is specifically employed in facilitating key transformations such as amination, arylation, and etherification of aryl chlorides, making it essential in the preparation of active palladium catalysts for forming carbon-carbon (C-C), carbon-nitrogen (C-N), and carbon-oxygen (C-O) bonds. Additionally, it is effectively utilized in the Pd-catalyzed α-arylation of azlactones, as well as esters, amides, and aldehydes, demonstrating its versatility in complex organic synthesis, including prominent reactions like the Heck and Suzuki couplings.
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