CAS 5144-89-8 1,10-Phenanthroline monohydrate, 99%

Synonyms

ZX-AT006983; SCHEMBL3790396; KSC269G7H; UNII-KSX215X00E; 1,10-phenanthroline-hydrate; TL8003406; 1,10-Phenanthroline hydrate; AX8021147; 1,10-Phenanthroline monohydrate, ACS reagent, 99%; TR-018323;

IUPAC Name

1,10-phenanthroline;hydrate;

Molecular Weight

198.225g/mol

Molecular Formula

C12H10N2O;

Canonical SMILES

C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O;

InChI

InChI=1S/C12H8N2.H₂O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2;

InChI Key

PPQJCISYYXZCAE-UHFFFAOYSA-N;

Melting Point

212 to 219 ° F (NTP, 1992);

Solubility

less than 0.1 mg/mL at 70° F (NTP, 1992);

Storage

Store at RT.

Complexity

183

Covalently-Bonded Unit Count

Exact Mass

198.079g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

198.079g/mol

Topological Polar Surface Area

26.8A^2

UNII

KSX215X00E

UN Number

2811

Application

1,10-Phenanthroline monohydrate, 99%, serves multiple purposes due to its unique properties as a white crystalline powder. It is primarily employed in studying DNA-protein interactions attributed to its nuclease activity, enhanced when complexed with copper. As a versatile chemical, it functions as a redox indicator and is instrumental in spectrophotometric assays, particularly for silver. Its capability as a chelating ligand is essential in the determination of metals such as iron, palladium, and vanadium. Additionally, it acts as a matrix metalloproteinase inhibitor and as a photometric reagent for iron by forming a red chelate with ferrous ions. Despite having a slight odor and being insoluble in water, 1,10-Phenanthroline hydrate forms complex compounds with ferrous ions but remains incompatible with strong oxidizers and acids, making it an indispensable tool in various chemical analyses and preparations of metal-chelate complexes.

February 4, 2025

Reliable Reagent for Advanced Research

1,10-Phenanthroline monohydrate from Alfa Chemistry has proven invaluable in studying DNA-protein interactions, particularly due to its effective nuclease activity when complexed with copper. Great for precise spectrophotometric assays and redox indicators.