CAS 1237588-12-3 MorDalphos - Catalysts / Alfa Chemistry

Synonyms

2-Morpholinophenyldi(1-adamantyl)phosphine; SC11165; bis(1-adamantyl)-(2-morpholin-4-ylphenyl)phosphane; Mor-DalPhos; 4-(2-(Di(adamantan-1-yl)phosphino)phenyl)morpholine; Di(1-adamantyl)-2-morpholinophenylphosphine; ZINC71773616; AK307802;

IUPAC Name

bis(1-adamantyl)-(2-morpholin-4-ylphenyl)phosphane;

Molecular Weight

463.646g/mol

Molecular Formula

C30H42NOP;

InChI

InChI=1S/C30H42NOP/c1-2-4-28(27(3-1)31-5-7-32-8-6-31)33(29-15-21-9-22(16-29)11-23(10-21)17-29)30-18-24-12-25(19-30)14-26(13-24)20-30/h1-4,21-26H,5-20H2;

InChI Key

CCBRRSUORFMQCZ-UHFFFAOYSA-N;

Storage

2-8°C

Complexity

632

Covalently-Bonded Unit Count

Exact Mass

463.3g/mol

H-Bond Acceptor

Heavy Atom Count

Monoisotopic Mass

463.3g/mol

Rotatable Bond Count

Topological Polar Surface Area

12.5A^2

MSDS

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COA

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Spec Sheet

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Application

P-N-ligand for use in the Pd-catalyzed cross-coupling of ammonia and hydrazine. Ref. (2) with a diverse range of sterically hindered, unbiased aryl chlorides. Low catalyst loading and mild conditions. Ref (5) with diamines in a chemoselective arylation process. Ref (6) with solvent-free or aqueous conditions.

P-N-ligand for the gold-catalyzed stereoselective hydroamination of internal alkynes with dialkylamines to afford E-amines.

P-N-ligand for use in the Pd-catalyzed for mono-α-arylation of ketones employing aryl chlorides, bromides, iodides, mesylates (Ref. 7) and tosylates.