CAS 153433-26-2 2-Chloro-1,3-dimethylimidazolinium Tetrafluoroborate

Molecular Weight

220.40

Molecular Formula

C5H10BClF4N2

Melting Point

175-177 °C(lit.)

Purity

98%+

Appearance

Solid

Application

2-Chloro-1,3-dimethylimidazolinium tetrafluoroborate is a versatile reagent, primarily used in the chemical synthesis field for its ability to facilitate esterification and peptide coupling without racemization, particularly targeting C-terminal amino acids and sterically hindered α,α-dimethyl amino acids. Its applications extend to the preparation of benzotriazol-1-yloxy derivatives, which are crucial for innovative coupling reactions. This colorless to white crystalline powder is also instrumental in synthesizing efficient diazo-transfer reagents and plays a critical role in the oxidative insertion process for creating palladium and nickel catalysts. Moreover, it is employed in the preparation of catalysts that are essential for various coupling reactions, highlighting its significance in advancing catalytic chemistry.

February 16, 2025

Exceptional Reagent for Esterification and Coupling

I utilized Alfa Chemistry's 2-Chloro-1,3-dimethylimidazolinium Tetrafluoroborate for peptide coupling and esterification in my research. Its effectiveness and reliability were outstanding, making complex reactions seamless and efficient. Highly recommend for advanced synthesis needs!